Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
IC50: 7nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
IC50: 7nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
IC50: 36nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
IC50: 110nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
BDBM501328(US11021493, Example 247 | US11021493, Example 251)
IC50: 3.38E+4nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair