Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 16 hits in this display
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 5nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 6nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 7nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 11nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 11nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 44nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 97nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 108nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 222nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 380nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 8.63E+4nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 1.07E+5nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
BDBM501192(US11021493, Example 111 | US11021493, Example 143 ...)
IC50: 1.51E+5nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair