Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 24 hits in this display
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 48nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 49nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 65nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 66nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 70nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 80nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 124nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 133nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 168nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 184nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 198nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 732nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 907nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 1.12E+3nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 2.63E+3nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 2.88E+3nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 4.11E+4nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 5.96E+4nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 2.23E+5nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 4.28E+5nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
BDBM501220(US11021493, Example 139 | US11021493, Example 147 ...)
IC50: 6.98E+5nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair