Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300228((2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)...)
Affinity DataKi:  740nMAssay Description:Inhibition of human cathepsin D preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300228((2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)...)
Affinity DataIC50:  605nMAssay Description:Inhibition of BACE1 mediated human Swedish amyloid precursor protein peptide hydrolysis by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300228((2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of BACE1 mediated hydrolysis of human amyloid precursor protein with Swedish and London mutation in HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed