Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50314608(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoro...)Copy SMILESCopy InChI

Affinity DataIC50:  140nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50314608(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoro...)Copy SMILESCopy InChI

Affinity DataIC50:  250nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50314608(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoro...)Copy SMILESCopy InChI

Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI