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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 100nM
Assay Description:
Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 220nM
Assay Description:
Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 3
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 230nM
Assay Description:
Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
Inhibition of HDAC10 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 5.30E+3nM
Assay Description:
Inhibition of HDAC5 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of human ERG expressed in CHO cells by patch clamp method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 9.00E+3nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 1.30E+4nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 2.10E+4nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
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Affinity Data
IC50: 2.80E+4nM
Assay Description:
Inhibition of CYP1A2 in human liver microsomes in presence of NADPH by LC-MS/MS method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of HDAC6 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 7
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of HDAC7 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 11
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of HDAC11 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of HDAC8 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 9
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.30E+4nM
Assay Description:
Inhibition of HDAC9 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 4
(Homo sapiens (Human))
Roche R & D Center China
Curated by
ChEMBL
Ligand
BDBM50399004
(CHEMBL2177582)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.60E+4nM
Assay Description:
Inhibition of HDAC4 using p53 (379 to 382 residues) based fluorogenic peptide substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI