Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HDAC10 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of HDAC5 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC6 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC7 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC11 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC8 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of HDAC9 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of HDAC4 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed