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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histamine H4 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50356886
(CHEMBL1915346)
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Affinity Data
Ki: 39nM
Assay Description:
Antagonist activity at full length human H4R expressed in HEK293 cells assessed as reversal of forskolin-induced cAMP production by CRE-beta-lactamas...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50356886
(CHEMBL1915346)
Copy SMILES
Copy InChI
Affinity Data
Ki: 83nM
Assay Description:
Displacement of [3H]-histamine from full length human H4R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50356886
(CHEMBL1915346)
Copy SMILES
Copy InChI
Affinity Data
Ki: 83nM
Assay Description:
Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in CHO cells coexpressing Ga15 by radioligand filtration binding...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50356886
(CHEMBL1915346)
Copy SMILES
Copy InChI
Affinity Data
Ki: 145nM
Assay Description:
Antagonist activity at human histamine H4 receptor expressed in HEK293 cells assessed as rev inhibition of forskolin-stimulated cAMP accumulation by ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50356886
(CHEMBL1915346)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.55E+4nM
Assay Description:
Binding affinity to human histamine H3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI