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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130414(US8822505, 14 | US8822505, 16)
Affinity DataIC50:  0.525nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130414(US8822505, 14 | US8822505, 16)
Affinity DataIC50:  0.613nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130414(US8822505, 14 | US8822505, 16)
Affinity DataIC50:  12.5nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130414(US8822505, 14 | US8822505, 16)
Affinity DataIC50:  39.8nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent