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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cathepsin S
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM130414
(US8822505, 14 | US8822505, 16)
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Copy InChI
Affinity Data
IC50: 0.525nM
pH: 6.5
Assay Description:
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM130414
(US8822505, 14 | US8822505, 16)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.613nM
pH: 6.5
Assay Description:
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM130414
(US8822505, 14 | US8822505, 16)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12.5nM
pH: 6.5
Assay Description:
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM130414
(US8822505, 14 | US8822505, 16)
Copy SMILES
Copy InChI
Affinity Data
IC50: 39.8nM
pH: 6.5
Assay Description:
Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI