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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: 0.0800nM
Assay Description:
Inhibition of full length human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells using FLUOR DE LYS as substrate preincubated for 3 hrs follo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Histone deacetylase 3
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: 0.0870nM
Assay Description:
Inhibition of human recombinant full length FLAG-tagged HDAC3 expressed in HEK293F cells in using BML-KI104 as substrate in presence of SAHA as inhib...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Nuclear receptor corepressor 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: 0.0870nM
Assay Description:
Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Article
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.100nM
Assay Description:
Inhibition of human recombinant full length FLAG-tagged HDAC1 expressed in HEK293F cells using BML-KI104 as substrate in presence of SAHA as inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC sid
In Depth
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Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: 0.470nM
Assay Description:
Inhibition of full length human recombinant FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using FLUOR DE LYS as substrate preincubate...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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In Depth
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Article
PubMed
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Target
Histone deacetylase 8
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of human recombinant HDAC8 expressed in Escherichia coli using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
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In Depth
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Target
Histone deacetylase 6
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: >4.50E+4nM
Assay Description:
Inhibition of HDAC6 (unknown origin) using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addition and measured after 60 mins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Histone deacetylase 4
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of HDAC4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Histone deacetylase 5
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of human recombinant full length N-terminal GST-tagged HDAC5 expressed in baculovirus infected sf9 insect cells using Boc-Lys(TFA)-AMC as ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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In Depth
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Target
Histone deacetylase 7
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of HDAC7 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
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In Depth
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Article
PubMed
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Target
Histone deacetylase 11
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of human recombinant untagged HDAC11 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(TFA)-AMC as substrate preincubated f...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
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PC sid
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Article
PubMed
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Target
Histone deacetylase 1/2/3/8
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544211
(CHEMBL4641682)
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Affinity Data
EC50: 4.70nM
Assay Description:
Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
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Article
PubMed
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