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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Histamine H4 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50304527
(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
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Affinity Data
Ki: 20nM
Assay Description:
Displacement of [3H]histamine from human histamine H4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50304527
(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 98nM
Assay Description:
Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50304527
(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 63nM
Assay Description:
Agonist activity at histamine H4 receptor (unknown origin) expressed in human U2OS cells increase in beta-arrestin2 recruitment after 2 hrs by lumine...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50304527
(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 13nM
Assay Description:
Agonist activity at histamine H4 receptor (unknown origin) expressed in HEK293T cells harboring CRE-luciferase after 6 hrs by luciferase reporter gen...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI