Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  0.457nMAssay Description:Displacement of [3H]granisetron from 5HT3A receptor expressed in HEK293 cells after 24 hrs by scintillation counting in presence of quipazineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  3nMAssay Description:Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  3nMAssay Description:Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  410nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  6.92E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed