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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Jagiellonian University
Curated by
ChEMBL
Ligand
BDBM189352
(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
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Affinity Data
Ki: 20nM
Assay Description:
Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM189352
(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
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Affinity Data
Ki: 5.60E+3nM
Assay Description:
Displacement of [3H]histamine from human H4R expressed in Sf9 cell membranes co-expressed with G protein Gai2 and Gb1gamma2 incubated for 60 mins by ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM189352
(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
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Copy InChI
Affinity Data
Ki: 5.60E+3nM ΔG°: -27.9kJ/mole
pH: 7.4 T: 2°C
Assay Description:
Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI