Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [3H]histamine from human H4R expressed in Sf9 cell membranes co-expressed with G protein Gai2 and Gb1gamma2 incubated for 60 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
Affinity DataKi:  5.60E+3nM ΔG°:  -27.9kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed