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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: 0.370nM
Assay Description:
Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: 0.370nM
Assay Description:
Displacement of [3H]-BRL 43694 from 5-HT3 receptor in rat cortex membrane incubated for 30 mins by liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: 43nM
Assay Description:
Inhibition of radiolabeled [3H]-Ketanserin ligand binding to 5-hydroxytryptamine 2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: 89nM
Assay Description:
Inhibition of radiolabeled [3H]-8-OH-DPAT ligand binding to 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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CHEMBL
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: 232nM
Assay Description:
Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Ligand Info
CHEMBL
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: 780nM
Assay Description:
Inhibition of radiolabeled [3H]mesulergine ligand binding to 5-hydroxytryptamine 2C receptor
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Target Info
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KEGG
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CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 4
(RAT)
Universit£
Curated by
ChEMBL
Ligand
BDBM50060686
(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of radiolabeled [3H]GR-113808 ligand binding to 5-hydroxytryptamine 4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
GoogleScholar
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CHEMBL
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PC sid
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Article
PubMed
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