Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone deacetylase 2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511246(CHEMBL4443980)
Affinity DataIC50:  251nMAssay Description:Inhibition of HDAC2 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511246(CHEMBL4443980)
Affinity DataIC50:  780nMAssay Description:Inhibition of HDAC6 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511246(CHEMBL4443980)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511246(CHEMBL4443980)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed