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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM130674(US8829200, 8)
Affinity DataIC50:  7.40nMT: 2°CAssay Description:Compounds are assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM130674(US8829200, 8)
Affinity DataIC50:  94nMAssay Description:Inhibition of FLAP in human whole blood assessed as reduction of LTB4 formation preincubated with enzyme for 15 mins followed by calcimycin addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed