Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50443727(CHEMBL3093882 | US9238658, 2)Copy SMILESCopy InChI

Affinity DataIC50:  170nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using Stearoyl-[9,10-3H]-CoA as substrate assessed as [3H2O] generationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50443727(CHEMBL3093882 | US9238658, 2)Copy SMILESCopy InChI

Affinity DataIC50:  170nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI