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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
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Affinity Data
Ki: 13nM
Assay Description:
Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
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Affinity Data
Ki: 40nM ΔG°: -43.9kJ/mole
pH: 7.4 T: 2°C
Assay Description:
Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...
More data for this Ligand-Target Pair
Target Info
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Target
Hrh3 protein
(RAT)
Vrije Universiteit
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
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Affinity Data
Ki: 47.9nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
GoogleScholar
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Target
Hrh3 protein
(RAT)
Vrije Universiteit
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 63.1nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
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CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Hrh3 protein
(RAT)
Vrije Universiteit
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 68nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Rattus norvegicus (rat))
University College London
Curated by
ChEMBL
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
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Affinity Data
Ki: 70nM
Assay Description:
In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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Copy BDB DOI
Target
Hrh3 protein
(RAT)
Vrije Universiteit
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 70nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 77.6nM
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
Details
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 84nM
Assay Description:
Binding affinity to the human histamine H3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 84nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 180nM
Assay Description:
Binding affinity to the human histamine H4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 180nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hrh3 protein
(RAT)
Vrije Universiteit
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 180nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.03E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig))
Hoechst Pharmaceutical Research Laboratories
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(RAT)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI