Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 42 hits in this display
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Ki: 5nMAssay Description:Binding affinity against alpha 2-Adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]clonidineMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Ki: 160nMAssay Description:Displacement of [3H]RS-79948-197 from recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane by scintillation counting methodMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Ki: 200nMAssay Description:Compound was evaluated for inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat forebrain homogenate.More data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Ki: 720nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Ki: 2.00E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]- WB-4101More data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Ki: 3.00E+3nMAssay Description:Binding affinity against beta-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of Dihydro-[3H]-alprenololMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
IC50: 8nMAssay Description:Inhibition of [3H]p-aminoclonidine (PAC) binding to alpha-2 adrenergic receptor of purified human platelet plasma membranesMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM44818(2,3-bis(oxidanyl)butanedioic acid;4-[(1R)-2-(methy...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM44818(2,3-bis(oxidanyl)butanedioic acid;4-[(1R)-2-(methy...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
EC50: 49nMAssay Description:Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as [3H]cAMP levels by radiolabeled ligand based assayMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
EC50: 400nMAssay Description:Beta-1 adrenergic receptor agonist activity by stimulation of contraction rate of isolated guinea pig atrial preparationsMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
EC50: 260nMAssay Description:Agonistic potency at beta-1 adrenergic receptor for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM44818(2,3-bis(oxidanyl)butanedioic acid;4-[(1R)-2-(methy...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM44818(2,3-bis(oxidanyl)butanedioic acid;4-[(1R)-2-(methy...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
EC50: 75nMAssay Description:Agonist activity at human alpha1 beta adrenergic receptor expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium influx by m...More data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
EC50: 290nMAssay Description:Agonist activity at human beta1 adrenergic receptor expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium influx by measuri...More data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
EC50: 30nMAssay Description:Agonist activity at recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
BDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)