Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM318840((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...)
BDBM318840((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...)
IC50: 11nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM318840((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...)
IC50: 12nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM318839(6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...)
IC50: 24nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM318839(6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...)
IC50: 29nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM318839(6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...)
IC50: 31nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM318840((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...)
BDBM318839(6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...)
IC50: 1.14E+4nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair