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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: 400nM
Assay Description:
Inhibition of wild-type human partial length AXL (R497 to Y821 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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Article
PubMed
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: 530nM
Assay Description:
Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: 600nM
Assay Description:
Inhibition of wild-type human partial length RET (E713 to D1014 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of wild-type human partial length SRC (L240 to L536 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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Article
PubMed
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Target
Aurora kinase A
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of human partial length Aurora A (E122 to K401 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as substrate i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of wild-type human partial length MER (R557 to L884 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Article
PubMed
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Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of wild-type human partial length TYRO3 (S497 to T814 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
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antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of wild-type human partial length VEGFR2 (R787 to P1253 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of wild-type human partial length MET (D1010 to S1367 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of AKT (unknown origin) using poly [Glu, Try] 4:1 as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of wild-type human partial length MTOR (L1382 to W2549 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as sub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50455353
(CHEMBL4210084)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of wild-type human partial length KIT (I571 to D952 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI