Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL

LigandBDBM50409761(CHEMBL2112863)Copy SMILESCopy InChI

Affinity DataKi:  17.6nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL

LigandBDBM50409761(CHEMBL2112863)Copy SMILESCopy InChI

Affinity DataIC50:  157nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL

LigandBDBM50085821(CHEMBL168427 | Phosphoric acid mono-[4-(6-methylam...)Copy SMILESCopy InChI

Affinity DataIC50:  157nMAssay Description:Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghostsMore data for this Ligand-Target Pair

Target InfoMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI