Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824](Homo sapiens (Human))
Novartis

US Patent

LigandBDBM355883((S)-1-(2-fluoro-7-(1-methoxyethyl)pyrazolo[1,5-a]p...)Copy SMILESCopy InChI

Affinity DataIC50:  0.00800nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Novartis

US Patent

LigandBDBM355883((S)-1-(2-fluoro-7-(1-methoxyethyl)pyrazolo[1,5-a]p...)Copy SMILESCopy InChI

Affinity DataIC50:  0.00800nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI