Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent

LigandBDBM50502726(CHEMBL4583328 | US11479539, Compound 55)Copy SMILESCopy InChI

Affinity DataEC50:  14nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL

LigandBDBM50502726(CHEMBL4583328 | US11479539, Compound 55)Copy SMILESCopy InChI

Affinity DataEC50:  14nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI