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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataKi:  0.600nMAssay Description:Time-dependent inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide preincubated for 3 hrs by Dix...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataKi:  0.600nMAssay Description:Time-dependent inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide preincubated for 6 hrs by Dix...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataKi:  0.700nMAssay Description:Time-dependent inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide preincubated for 1 hr by Dixo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataKi:  5.10nMAssay Description:Inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylesterase 1D(Mus musculus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataIC50:  500nMAssay Description:Competitive inhibition of mouse heart membrane TGH preincubated for 6 hrs followed by FP-rhodamine addition measured after 10 mins by fluorescence sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataIC50: >1.00E+5nMAssay Description:Competitive inhibition of mouse brain membrane MAGL preincubated for 6 hrs followed by FP-rhodamine addition measured after 10 mins by fluorescence s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataIC50: >1.00E+5nMAssay Description:Competitive inhibition of mouse brain membrane ABHD6 preincubated for 6 hrs followed by FP-rhodamine addition measured after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50448895(CHEMBL3125310)
Affinity DataIC50: >1.00E+5nMAssay Description:Competitive inhibition of mouse brain membrane KIAA1363 preincubated for 6 hrs followed by FP-rhodamine addition measured after 10 mins by fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed