Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.20nM
Assay Description:
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 170nM
Assay Description:
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.15E+3nM
Assay Description:
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
American Cyanamid
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Compound was evaluated for its binding affinity towards Beta-2 adrenergic receptor in rat soleus membrane by displacing (-)-isoproterenol (50 microM)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
American Cyanamid
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 59nM
Assay Description:
Compound was evaluated for its binding affinity towards Beta-1 adrenergic receptor in rat heart membrane by displacing [125I]- iodocyanopindolol
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
American Cyanamid
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 500nM
Assay Description:
Compound was evaluated in vitro for beta-adrenergic activity against beta-1 adrenergic receptor by the inhibition of insulin stimulated [14C]- glucos...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Rattus norvegicus)
American Cyanamid
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 16nM
Assay Description:
Compound was evaluated in vitro for beta-adrenergic activity against beta-3 adrenergic receptor in rat epididymal fat pads by stimulation of glycerol...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 420nM
Assay Description:
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI