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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
41
hits in this display
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
Assay Description:
Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibition of human VEGFR2 expressed in Sf9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibition of human VEGFR3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of human VEGFR3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Mus musculus)
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of mouse GST-fused VEGFR2 expressed in Sf9 insect cells after 20 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of human Lck
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of human Lck
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of human PDGFRalpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of human GST-fused VEGFR2 expressed in Sf9 insect cells after 20 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Inhibition of human Flt3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Inhibition of human Flt3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
Inhibition of human VEGFR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37nM
Assay Description:
Inhibition of human FGFR2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 38nM
Assay Description:
Inhibition of human FGFR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 59nM
Assay Description:
Inhibition of human PDGFRalpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 65nM
Assay Description:
Inhibition of human PDGFRbeta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 69nM
Assay Description:
Inhibition of human FGFR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 104nM
Assay Description:
Inhibition of human VEGFR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 108nM
Assay Description:
Inhibition of human FGFR3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 156nM
Assay Description:
Inhibition of human Src
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 156nM
Assay Description:
Inhibition of human Src
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 195nM
Assay Description:
Inhibition of human Lyn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 195nM
Assay Description:
Inhibition of human Lyn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 610nM
Assay Description:
Inhibition of human FGFR4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+3nM
Assay Description:
Inhibition of human IGF1R
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+3nM
Assay Description:
Inhibition of human insulin receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CDK4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human HER2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human InsR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human IGFR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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CHEMBL
MMDB
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human Plk1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CDK4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CDK1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CDK1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of human EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of human HER2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Boehringer Ingelheim Austria
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
Kd: 3.80nM
Assay Description:
Binding affinity to human FLT3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Califia Bio
Curated by
ChEMBL
Ligand
BDBM50279080
((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
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Affinity Data
Kd: 700nM
Assay Description:
Binding affinity to human MLK3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI