Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCaspase-3(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL

LigandBDBM50031591(CHEMBL3359183)Copy SMILESCopy InChI

Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCaspase-7(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL

LigandBDBM50031591(CHEMBL3359183)Copy SMILESCopy InChI

Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI