Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM439300
(US10604534, Example 17)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.30nM
Assay Description:
BACE1: Reagents: Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE1 catalytic domain (>95% pure); A...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM439300
(US10604534, Example 17)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.90nM
Assay Description:
BACE-2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI