Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50374253(CHEMBL403195)Copy SMILESCopy InChI

Affinity DataIC50:  0.700nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50374253(CHEMBL403195)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50374253(CHEMBL403195)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Inhibition of BACE1 in human HEK293 cells assessed as inhibition of amyloid beta 40 productionMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
Copy BDB DOI