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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone acetyltransferase KAT7(Homo sapiens)
Epizyme

US Patent
LigandPNGBDBM606414(US11685732, Compound I-62)
Affinity DataIC50: <1.00E+4nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM606414(US11685732, Compound I-62)
Affinity DataIC50:  3.00E+4nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM606414(US11685732, Compound I-62)
Affinity DataIC50:  3.00E+4nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Epizyme

US Patent
LigandPNGBDBM606414(US11685732, Compound I-62)
Affinity DataIC50:  3.00E+4nMAssay Description:KAT-6A. Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent