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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50247165
(CHEMBL4077366)
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Affinity Data
Ki: 102nM
Assay Description:
Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50247165
(CHEMBL4077366)
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Affinity Data
EC50: 562nM
Assay Description:
Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50247165
(CHEMBL4077366)
Copy SMILES
Copy InChI
Affinity Data
EC50: 16nM
Assay Description:
Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50247165
(CHEMBL4077366)
Copy SMILES
Copy InChI
Affinity Data
EC50: 681nM
Assay Description:
Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI