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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 4.56nM
Assay Description:
Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyser
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Target
Alpha-2C adrenergic receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 154nM
Assay Description:
Inhibition of human cloned alpha2C adrenergic receptor by competitive binding experiment
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Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 497nM
Assay Description:
Inhibition of human cloned 5-HT2C receptor by competitive binding experiment
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Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 559nM
Assay Description:
Inhibition of human cloned 5HT2B receptor by competitive binding experiment
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Target
Histamine H1 receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 665nM
Assay Description:
Inhibition of human cloned histamine H1 receptor by competitive binding experiment
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 731nM
Assay Description:
Inhibition of human cloned 5HT7 receptor by competitive binding experiment
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Target
Histamine H2 receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 827nM
Assay Description:
Inhibition of human cloned histamine H2 receptor by competitive binding experiment
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Target
D(4) dopamine receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 923nM
Assay Description:
Inhibition of human cloned dopamine D4 receptor by competitive binding experiment
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 1.01E+3nM
Assay Description:
Inhibition of human cloned SERT by competitive binding experiment
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Target
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 1.68E+3nM
Assay Description:
Inhibition of human cloned 5HT5A receptor by competitive binding experiment
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 1.88E+3nM
Assay Description:
Inhibition of human cloned 5HT1A receptor by competitive binding experiment
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Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 1.93E+3nM
Assay Description:
Inhibition of human cloned dopamine D1 receptor by competitive binding experiment
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Target
Mu-type opioid receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 2.01E+3nM
Assay Description:
Inhibition of human cloned mu opioid receptor by competitive binding experiment
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Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 3.36E+3nM
Assay Description:
Inhibition of human cloned 5HT1B receptor by competitive binding experiment
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Target
Histamine H3 receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: 9.03E+3nM
Assay Description:
Inhibition of human cloned histamine H3 receptor by competitive binding experiment
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human cloned 5HT6 receptor by competitive binding experiment
More data for this Ligand-Target Pair
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Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human cloned beta3 adrenergic receptor by competitive binding experiment
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human cloned 5HT1E receptor by competitive binding experiment
More data for this Ligand-Target Pair
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human cloned dopamine D2 receptor by competitive binding experiment
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by
ChEMBL
Ligand
BDBM50267554
(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-to...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human cloned 5HT3 receptor by competitive binding experiment
More data for this Ligand-Target Pair
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