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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Coagulation factor VII
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
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Affinity Data
Ki: 7nM ΔG°: -46.1kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor VII
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7nM ΔG°: -46.1kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Bos taurus (bovine))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
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Copy InChI
Affinity Data
Ki: 80nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Bos taurus (bovine))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 80nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
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Copy InChI
Affinity Data
Ki: 6.40E+3nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.40E+3nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90E+4nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13555
((2S)-2-{2-[4-(benzyloxy)-5-methoxy-2-(2-phenylacet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90E+4nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI