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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50056415
(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
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Affinity Data
Ki: 3.98nM
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50056415
(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
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Copy InChI
Affinity Data
Ki: 19nM
Assay Description:
Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 mins
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Target
5-hydroxytryptamine receptor 4
(RAT)
Cnrs-Biocis
Curated by
ChEMBL
Ligand
BDBM50056415
(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
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Affinity Data
Ki: 28nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand
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Target Info
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50056415
(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
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Affinity Data
Ki: 2.00E+3nM
Assay Description:
Binding affinity at 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50056415
(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
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Affinity Data
IC50: 49nM
Assay Description:
Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...
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Target Info
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Reactome pathway
UniProtKB/SwissProt
antibodypedia
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50056415
(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 30nM
Assay Description:
5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI