Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetCytochrome P450 2C8(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of CYP2B6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFree fatty acid receptor 4(Homo sapiens)
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50543519(CHEMBL4642324)
Affinity DataEC50:  71nMAssay Description:Modulation of GPR120 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50543519(CHEMBL4642324)
Affinity DataEC50:  71nMAssay Description:Modulation of GPR40 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50244064(CHEMBL4094183)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50243975(CHEMBL4080226)
Affinity DataEC50:  3.60E+3nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails PubMed