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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: 2.10nM
Assay Description:
Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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Article
PubMed
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Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: 21nM
Assay Description:
Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligand
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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CHEMBL
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Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: 220nM
Assay Description:
Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: 4.00E+3nM
Assay Description:
Compound was tested for the Binding affinity against N1e-115 neuroblastoma 5-hydroxytryptamine 3 receptor by Radio ligand [3H]-GR-65,630 binding assa...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Ligand Info
CHEMBL
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Article
PubMed
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Target
Muscarinic acetylcholine receptor M1
(RAT)
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: 5.40E+3nM
Assay Description:
Compound was tested for the Binding affinity against rat cortical Muscarinic acetylcholine receptor M1 by Radio ligand [3H]-pirenzepine binding assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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CHEMBL
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Article
PubMed
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Target
Muscarinic acetylcholine receptor M2
(RAT)
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: 7.30E+3nM
Assay Description:
Compound was tested for the Binding affinity against rat heart Muscarinic acetylcholine receptor M2 by Radio ligand [3H]-quinuclidinyl binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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B.MOAD
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Compound was tested for the Binding affinity against Human cloned Dopamine receptor D1 by Radio ligand ([3H]-SCH-23390) binding assay
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Article
PubMed
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Target
Histamine H1 receptor
(RAT)
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Compound was tested for the Binding affinity against rat cortical H1 receptor by Radio ligand [3H]-pyrilamine binding assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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CHEMBL
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PC sid
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Article
PubMed
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Target
D(1B) dopamine receptor
(Homo sapiens (Human))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Compound was tested for the Binding affinity against Human cloned Dopamine receptor D5 by Radio ligand ([3H]-SCH-23390) binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Compound was tested for the Binding affinity against rat hippocampal 5-hydroxytryptamine 1A receptor by Radio ligand [3H]-8-OH-DPAT binding assay.
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50052180
(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Compound was tested for the Binding affinity against rat frontal cortex 5-hydroxytryptamine 2A receptor by Radio ligand [3H]-ketanserin binding assay...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI