Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCytochrome P450 1A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50252422(CHEBI:63672 | CHEMBL498917)
Affinity DataKi:  130nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after 15 mins in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50252422(CHEBI:63672 | CHEMBL498917)
Affinity DataKi:  900nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after 15 mins in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50252422(CHEBI:63672 | CHEMBL498917)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50252422(CHEBI:63672 | CHEMBL498917)
Affinity DataIC50:  4.01E+3nMAssay Description:Inhibition of recombinant human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails PubMed