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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Celgene Car
US Patent
Ligand
BDBM94679
(US10189794, Compound I-124 | US10618902, Compound ...)
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Affinity Data
IC50: <100nM
pH: 7.5
Assay Description:
Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. a) [FGFR4-WT]=10 nM, [ATP]=300 uM, [Y10-Sox]=10 uM (ATP KMapp 300 uM): A 10x stock...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Celgene Car
US Patent
Ligand
BDBM94679
(US10189794, Compound I-124 | US10618902, Compound ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
For MDA-MB-453 cells signaling, cells were grown in 96-well poly-D-lysine plates (BD Bioscience, San Jose, Calif.) to 90% confluence, and were then i...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Celgene Car
US Patent
Ligand
BDBM94679
(US10189794, Compound I-124 | US10618902, Compound ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
A 10× stock solution of FGFR4-WT (PR4380C), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 7, was prepared as described below...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Celgene Car
US Patent
Ligand
BDBM94679
(US10189794, Compound I-124 | US10618902, Compound ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <500nM
Assay Description:
A 10× stock solution of FGFR4-WT (PR4380C or P3054), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 10, was prepared as descr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI