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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Principia Biopharma
US Patent
Ligand
BDBM286996
(8-(2-((1-acryloylpiperidin-4-yl)oxy)ethyl)-2-((cyc...)
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Affinity Data
IC50: 1.90nM
T: 2°C
Assay Description:
A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Principia Biopharma
US Patent
Ligand
BDBM286996
(8-(2-((1-acryloylpiperidin-4-yl)oxy)ethyl)-2-((cyc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90nM
Assay Description:
A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Principia Biopharma
US Patent
Ligand
BDBM286996
(8-(2-((1-acryloylpiperidin-4-yl)oxy)ethyl)-2-((cyc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90nM
Assay Description:
A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Principia Biopharma
US Patent
Ligand
BDBM286996
(8-(2-((1-acryloylpiperidin-4-yl)oxy)ethyl)-2-((cyc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16.3nM
Assay Description:
A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Principia Biopharma
US Patent
Ligand
BDBM286996
(8-(2-((1-acryloylpiperidin-4-yl)oxy)ethyl)-2-((cyc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16.3nM
Assay Description:
The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI