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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  78nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC10 expressed in baculovirus infected Sf9 insect cells using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human His-tagged HDAC1 expressed in insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured after 30 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  106nMAssay Description:Inhibition of recombinant human GST-fused HDAC3/NCOR1 (397 to 503 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  136nMAssay Description:Inhibition of human full-length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  404nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys(Tfa)-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50:  688nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC5 expressed in baculovirus infected Sf9 insect cells using AcLeu-Gly-Lys(Tfa)-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC9 (1 to 1069 residues) expressed in wheat germ expression system using Ac-Leu-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) using AcLeu-Gly-Lys(Tfa)-AMC as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged HDAC11 expressed in baculovirus infected Sf9 insect cells using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Shenzhen Technology University

Curated by ChEMBL
LigandPNGBDBM50565548(CHEMBL4790998)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC4 (627 to end residues) expressed in baculovirus infected Sf9 insect cells using AcLeu-Gly-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed