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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Federal University Of Parana

Curated by ChEMBL
LigandPNGBDBM50085526((E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5...)
Affinity DataIC50:  160nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in human HEK293 cells assessed as reversal of BCRP-mediated mitoxantrone resistance and measured after...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Federal University Of Parana

Curated by ChEMBL
LigandPNGBDBM50085526((E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5...)
Affinity DataIC50:  160nMAssay Description:Inhibition of wildtype ABCG2 (unknown origin) transfected in HEK293 cells measured after 30 mins by flow cytometric anlaysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085526((E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5...)
Affinity DataIC50:  750nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes epressing human cytochrome P450 1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085526((E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes expressing human cytochrome P450 1B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50085526((E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5...)
Affinity DataIC50:  3.71E+4nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) using N-methyldihydronicotinamide as co-substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085526((E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5...)
Affinity DataIC50:  5.70E+5nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes expressing human cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed