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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Activin receptor type-1
(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50544418
(CHEMBL4648102)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Activin receptor type-1
(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50544418
(CHEMBL4648102)
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Copy InChI
Affinity Data
IC50: 31nM
Assay Description:
Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Activin receptor type-1B
(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50544418
(CHEMBL4648102)
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Affinity Data
IC50: 1.36E+3nM
Assay Description:
Inhibition of human ALK4 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50544418
(CHEMBL4648102)
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Affinity Data
IC50: 1.91E+3nM
Assay Description:
Inhibition of recombinant human ALK5 expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter after 24 hrs by dual ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50544418
(CHEMBL4648102)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.85E+3nM
Assay Description:
Inhibition of human ALK5 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50544418
(CHEMBL4648102)
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Affinity Data
IC50: 8.10E+3nM
Assay Description:
Inhibition of human ERG expressed in HEK293 cells after 5 mins by IonWorks barracuda patch clamp method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI