Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380674((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
BDBM380673(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-1...)
IC50: 31.5nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380674((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
IC50: 51.5nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380673(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-1...)
IC50: 53.5nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380673(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-1...)
IC50: 96nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380674((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
IC50: 100nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380674((R)-6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-y...)
BDBM380673(6-(4-chlorophenyl)-2-(3,6-dihydro-2H-pyran-4-yl)-1...)
IC50: 2.19E+4nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair