Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50:  59nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human C-terminal polyhistidine-tagged cathepsin B (Arg18 to Ile339 residues) expressed in HEK293 cells using Z-Leu-Arg-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human C-terminal polyhistidine-tagged cathepsin S (Met1 to Ile331 residues) expressed in HEK293 cells using MCA-Arg-Pro-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)

Curated by ChEMBL
LigandPNGBDBM50525282(CHEMBL4464752)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged cathepsin L (Glu113 to Val333 and Ala114 to Val333 residues) expressed in mouse myeloma cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed