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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-4
(Homo sapiens (Human))
University Of Turin
Curated by
ChEMBL
Ligand
BDBM50088456
(1-(6-Chloro-5-methoxy-pyridin-3-yl)-[1,4]diazepane...)
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Affinity Data
IC50: 0.676nM
Assay Description:
Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Neurosearch
Curated by
ChEMBL
Ligand
BDBM50088456
(1-(6-Chloro-5-methoxy-pyridin-3-yl)-[1,4]diazepane...)
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Copy InChI
Affinity Data
IC50: 0.680nM
Assay Description:
In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Homo sapiens (Human))
University Of Turin
Curated by
ChEMBL
Ligand
BDBM50088456
(1-(6-Chloro-5-methoxy-pyridin-3-yl)-[1,4]diazepane...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 91.2nM
Assay Description:
Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI