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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Replicase polyprotein 1ab
(2019-nCoV)
Institut Pasteur Korea
Ligand
BDBM50241654
((+)-berbamine | Berbamine | CHEMBL504323)
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Affinity Data
IC50: 7.87E+3nM
Assay Description:
Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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CHEMBL
MCE
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Target
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50241654
((+)-berbamine | Berbamine | CHEMBL504323)
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Affinity Data
IC50: 2.20E+4nM
Assay Description:
Inhibition of calmodulin-dependent phosphodiesterase
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
MCE
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In Depth
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Article
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Target
Cholinesterase
(Homo sapiens (Human))
Charles University
Curated by
ChEMBL
Ligand
BDBM50241654
((+)-berbamine | Berbamine | CHEMBL504323)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human BuChE using butyrylthiocholine iodide as substrate measured for 1 min by Ellman's method
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Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
MCE
KEGG
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Charles University
Curated by
ChEMBL
Ligand
BDBM50241654
((+)-berbamine | Berbamine | CHEMBL504323)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MCE
KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
Prolyl endopeptidase
(Homo sapiens (Human))
Charles University
Curated by
ChEMBL
Ligand
BDBM50241654
((+)-berbamine | Berbamine | CHEMBL504323)
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Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of POP (unknown origin) using (Z)-Gly-Pro-p-nitroanilide as substrate preincubated for 5 mins followed by substrate addition and measured ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI