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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281308(CHEMBL4162911)
Affinity DataIC50:  22nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281308(CHEMBL4162911)
Affinity DataIC50:  413nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281308(CHEMBL4162911)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human GLP using histone H3 peptide as substrate after 120 mins in presence of [3H]SAM by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed