Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDual specificity mitogen-activated protein kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL

LigandBDBM50095235(6-Methoxy-7-(2-morpholin-4-yl-ethoxy)-4-(4-phenoxy...)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL

LigandBDBM50095235(6-Methoxy-7-(2-morpholin-4-yl-ethoxy)-4-(4-phenoxy...)Copy SMILESCopy InChI

Affinity DataIC50:  25nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI