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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
58
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 7.20nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 9nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
Ki: 9nM
Assay Description:
Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 DE...
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 9nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD2 BD1 (72 to 205 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 22nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 50nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD2 BD2 (349 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 61nM
Assay Description:
Inhibition of tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain1 after...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 75nM
Assay Description:
Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 2 (333 to 460 residues) expressed in Rosetta2 D...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
Ki: 75nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Ki: 385nM
Assay Description:
Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain2 after 60 mins by HTR...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISA
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of His/FLAG-tagged BRD4 BD1 (unknown origin) using histone H4-TetraAcetylated-biotin peptide as substrate incubated for 20 mins by AlphaLI...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of BRD4 bromodomain 1 (unknown origin)
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant expressed in Escher...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 25nM
Assay Description:
Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in E...
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Target
Isoform C of Bromodomain-containing protein 4 (Short)
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 29.4nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...
More data for this Ligand-Target Pair
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 DE...
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 32nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD3 BD1 (1 to 435 residues)/BD2 Y348A mutant expressed in Escher...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 36nM
Assay Description:
Displacement of Alexa Fluor 647 labelled ligand from His6-thr-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant (unknown origin) after 30 mins by ...
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 50nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD2 BD1 (1 to 473 residues)/BD2 Y386A mutant expressed in Escher...
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 79nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD3 BD2 (1 to 435 residues)/BD1 Y73A mutant expressed in Escheri...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 100nM
Assay Description:
Inhibition of BRD4(1) (unknown origin) incubated for 4 hrs by (+)-JQ1 fluorescent ligand based fluorescence anisotrophy
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 107nM
Assay Description:
Inhibition of BRD4 bromodomain-1 (unknown origin) by europium based LANCE TR-FRET assay
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Target
Bromodomain testis-specific protein
(Homo sapiens (Human))
Gsk
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 126nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRDT BD1 (1 to 397 residues)/BD2 Y309A mutant expressed in Escher...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 130nM
Assay Description:
Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrs
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 200nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD2 BD2 (1 to 473 residues)/BD1 Y113A mutant expressed in Escher...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 200nM
Assay Description:
Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced IL-6 secretion incubated for 18 to 24 hrs by MSD assay
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 226nM
Assay Description:
Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 226nM
Assay Description:
Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 2 (333 to 460 residues) expressed in Rosetta2 D...
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 250nM
Assay Description:
Inhibition of BRD3 (unknown origin) by fluorescence anisotrophy
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Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 251nM
Assay Description:
Binding affinity to BRD3 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysis
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 274nM
Assay Description:
Displacement of Alexa Fluor 647 labelled ligand from His6-tagged BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant (unknown origin) after 30 mins by TR-FR...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 316nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant expressed in Escheri...
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 500nM
Assay Description:
Inhibition of BRD2 (unknown origin) by fluorescence anisotrophy
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 501nM
Assay Description:
Binding affinity to human BRD2 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysis
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 790nM
Assay Description:
Inhibition of BRD4 (unknown origin) by fluorescence polarization assay
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 790nM
Assay Description:
Inhibition of BRD4 (unknown origin) by fluorescence anisotropy ligand displacement assay
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 790nM
Assay Description:
Inhibition of BRD4 (unknown origin) by fluorescence anisotrophy
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 794nM
Assay Description:
Binding affinity to BRD4 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysis
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 1.26E+3nM
Assay Description:
Inhibition of BRD4 in human whole blood assessed as reduction in LPS-induced IL-6 secretion preincubated for 30 mins followed by LPS stimulation and ...
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Target
Bromodomain testis-specific protein
(Homo sapiens (Human))
Gsk
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 1.59E+3nM
Assay Description:
Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRDT BD2 (1 to 397 residues)/BD1 Y66A mutant expressed in Escheri...
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Target
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 3.98E+3nM
Assay Description:
Inhibition of PDE4B
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 9.70E+3nM
Assay Description:
Inhibition of CYP3A4 using diethoxyfluoresin as substrate
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 9.70E+3nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in Escherichia coli using DEF as probe substrate incubated for 15 to 60 mins by fluorometric assay
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 9.70E+3nM
Assay Description:
Inhibition of CYP3A4
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 9.70E+3nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in Escherichia coli using VG as probe substrate incubated for 15 to 60 mins by fluorometric assay
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
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Affinity Data
IC50: 9.90E+3nM
Assay Description:
Inhibition of recombinant human CYP2C9 expressed in Escherichia coli using FCA as substrate incubated for 15 to 60 mins by fluorometric assay
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.90E+3nM
Assay Description:
Inhibition of CYP2C9
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
IC50: 9.90E+3nM
Assay Description:
Inhibition of CYP2C9
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Kd: 30nM
Assay Description:
Binding affinity to biotinylated BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Kd: 70nM
Assay Description:
Binding affinity to biotinylated BRD2 BD2 (349 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...
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Target
ATPase family AAA domain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding affinity to biotinylated ATAD2A (981 to 1108 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Kd: 55nM
Assay Description:
Binding affinity to biotinylated BRD2 BD1 (72 to 205 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...
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Target
CREB-binding protein
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
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Affinity Data
Kd: 3.08E+3nM
Assay Description:
Binding affinity to biotinylated CREBBP (1043 to 1159 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
Kd: 41nM
Assay Description:
Binding affinity to biotinylated BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
Kd: 215nM
Assay Description:
Binding affinity to biotinylated BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50380682
(CHEMBL2017291 | I-BET151 (16))
Copy SMILES
Copy InChI
Affinity Data
Kd: 53nM
Assay Description:
Binding affinity to biotinylated BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...
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