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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetBone morphogenetic protein 1(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50402510(CHEMBL2204087)
Affinity DataIC50:  10nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50402510(CHEMBL2204087)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PCP in HFF cells assessed as inhibition of collagen deposition after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50402510(CHEMBL2204087)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of para-amino phenylmercuric acetate-activated MMP2 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50402510(CHEMBL2204087)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of para-amino phenylmercuric acetate-activated MMP1 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50402510(CHEMBL2204087)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of para-amino phenylmercuric acetate-activated MMP9 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed